Imaging the Parathyroid Glands Using ^99mTc-tetrofosmin: Current Status

Imaging of parathyroid glands.

Preoperative imaging studies have an important role in facilitating successful localization of adenomas for surgeons. Their use has increased and parallels the recent growth of minimally invasive parathyroidectomy. Based on findings that scintigraphy is reported to have the highest accuracy for localization of adenomas when compared with anatomic imaging techniques, this article discusses the c...

Imaging of the Parathyroid Glands In

Hyperplasia of all four parathyroid glands in renal failure visualized by Tc-99m tetrofosmin scintigraphy.

Key words: hyperparathyroidism-radionuclide-imaging; primary and secondary hyperparathyroidism [1–3]. With hyperplastic parathyroid glands tetrofosmin hyperplasia; Technetium-99m-diagnostic use; tetrofosmin imaging gives an overall sensitivity of 84% and a specificity of 75%, higher than those of Tc-99m sestam-ibi, ultrasonography and magnetic resonance imaging Renal history [1–2]. The former h...

Parathyroid hormone without parathyroid glands.

In mammals, PTH is a component in a complex signaling system involving three structurally related ligands and two G protein-coupled receptors, which share significant amino acid sequence homology (Fig. 1). PTH is a peptide hormone comprising 84 amino acids that is made by the parathyroid glands (and to a much smaller extend by the thymus) and acts through the PTH/PTH-related peptide (PTHrP) rec...

Multimodality imaging of the thyroid and parathyroid glands.

Nuclear imaging of the thyroid and parathyroid glands has evolved from early radionuclide rectilinear thyroid scanning to the recently developed dual isotope subtraction technique for detecting parathyroid lesions. At the same time, x-ray fluorescent scanning, ultrasound, x-ray computed tomography, and magnetic resonance imaging have improved identification of these endocrine organs. The approp...